Over a 7-month study period 5.3 % of patients presenting for radiological investigation did not have a recent eGFR and required point-of-care creatinine measurement/ eGFR (total number of measurements 3087, i.e. This policy was recently implemented at Massachusetts General Hospital where researchers have conducted a study aimed at evaluating the impact, including cost effectiveness, of the policy. This allows rapid assessment of patient renal function within the department, immediately prior to radiological investigation. To address this problem some radiological departments have introduced, or are considering introducing, point-of-care creatinine testing. Measurement of plasma creatinine and calculation of estimated glomerular filtration rate (eGFR) provides the means for assessing renal function and it is important to have knowledge of recent eGFR for patients at risk of NSF and CIN before proceeding with administration of image-enhancing agent.īest safety practice demands that if recent eGFR is not available, the radiological investigation should be cancelled until plasma creatinine measurement is arranged and eGFR result is available. The risk only applies to those patients with renal disease, either acute kidney injury (AKI) or chronic kidney disease (CKD). ![]() The necessary administration of image-enhancing agents to patients prior to radiological investigation is associated with risk of two serious adverse effects: nephrogenic systemic fibrosis (NSF) and contrast-induced nephropathy (CIN).
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